diff --git a/Scripts/NodeGraph.cs b/Scripts/NodeGraph.cs
index 32310d2..e9fe75f 100644
--- a/Scripts/NodeGraph.cs
+++ b/Scripts/NodeGraph.cs
@@ -38,10 +38,16 @@ namespace XNode {
         public void RemoveNode(Node node) {
             node.ClearConnections();
             nodes.Remove(node);
+            if (Application.isPlaying) Destroy(node);
         }
 
         /// <summary> Remove all nodes and connections from the graph </summary>
         public void Clear() {
+            if (Application.isPlaying) {
+                for (int i = 0; i < nodes.Count; i++) {
+                    Destroy(nodes[i]);
+                }
+            }
             nodes.Clear();
         }
 
@@ -67,5 +73,10 @@ namespace XNode {
 
             return graph;
         }
+
+        private void OnDestroy() {
+            // Remove all nodes prior to graph destruction
+            Clear();
+        }
     }
 }
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